Breast Cancer Subtypes

Rodrigo Arrangoiz MS, MD, FACS, FSSO
  • One of the most important factors to be considered with breast cancer diagnosis is breast cancer subtype
  • There are three major breast cancer subtypes: luminal-like, HER2-positive, and triple-negative, which are identified by the expression of hormone receptors and HER2 by breast cancer cells
  • Of note, these subtypes have different biologic features, prognosis, and response to treatment
  • Although all breast cancers may recur despite treatment, those defined as triple-negative breast cancer (TNBC), which lack specific targets for effective treatments, are considered high risk
  • Hence, up to 40% of early-stage breast cancer patients will experience recurrence after standard treatment
  • Tumors expressing hormone receptors (ie, estrogen and progesterone receptors) are defined as luminal-like, are typically less aggressive, and have a good prognosis
  • HER2-positive breast tumors are biologically aggressive tumors, but the outcome has dramatically improved with anti-HER2 targeted therapies
#Arrangoiz #BreastSurgeon #CancerSurgeon #SurgicalOncologist #MountSinaiMedicalCenter #MSMC #Miami #Mexico #BreastCancer

Published by Rodrigo Arrangoiz MS, MD, FACS, FSSO

My name is Rodrigo Arrangoiz I am a breast surgeon/ thyroid surgeon / parathyroid surgeon / head and neck surgeon / surgical oncologist that works at Center for Advanced Surgical Oncology in Miami, Florida. I was trained as a surgeon at Michigan State University from (2005 to 2010) where I was a chief resident in 2010. My surgical oncology and head and neck training was performed at the Fox Chase Cancer Center in Philadelphia from 2010 to 2012. At the same time I underwent a masters in science (Clinical research for health professionals) at the University of Drexel. Through the International Federation of Head and Neck Societies / Memorial Sloan Kettering Cancer Center I performed a two year head and neck surgery and oncology / endocrine fellowship that ended in 2016. Mi nombre es Rodrigo Arrangoiz, soy cirujano oncólogo / cirujano de tumores de cabeza y cuello / cirujano endocrino que trabaja Center for Advanced Surgical Oncology en Miami, Florida. Fui entrenado como cirujano en Michigan State University (2005 a 2010 ) donde fui jefe de residentes en 2010. Mi formación en oncología quirúrgica y e n tumores de cabeza y cuello se realizó en el Fox Chase Cancer Center en Filadelfia de 2010 a 2012. Al mismo tiempo, me sometí a una maestría en ciencias (investigación clínica para profesionales de la salud) en la Universidad de Drexel. A través de la Federación Internacional de Sociedades de Cabeza y Cuello / Memorial Sloan Kettering Cancer Center realicé una sub especialidad en cirugía de cabeza y cuello / cirugia endocrina de dos años que terminó en 2016.

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