What is Primary Hyperparathyroidism?

  • Primary hyperparathyroidism (PHPT):
    • Arises from an unregulated overproduction of parathyroid hormone (PTH) from an abnormal parathyroid gland
    • Hypercalcemia or widely fluctuating levels of serum calcium resulting from:
      • The inappropriate or autogenous secretion of PTH:
        • By one or more parathyroid glands:
          • In the absence of a known or recognized stimulus
    • The most common cause of hypercalcemia in the outpatient setting is:
      • Primary hyperparathyroidism (PHPT)

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