Flat Epithelial Atypia

Rodrigo Arrangoiz MS, MD, FACS, FSSO
  • Flat epithelial atypia:
    • Confers a relative risk of developing breast cancer of:
      • Approximately 1.5
    • Excisional biopsy may be indicated if:
      • Calcifications are incompletely removed or 
      • If there is question of sampling error:
        • But excision to negative margins is not required
    • The probability of finding a concurrent invasive carcinoma is:
      • Approximately 1% to 5% when flat epithelial atypia is found on core needle biopsy:
        • Given the small (less than two-fold) associated increase in breast cancer risk:
          • Chemoprevention is not indicated nor is routine annual screening breast MRI
  • References:
    • Sudarshan M, Meguerditchian AN, Mesurolle B, Meterissian S. Flat epithelial atypia of the breast: characteristics and behaviors. Am J Surg. 2011;201(2)245-250.
    • Piubello Q, Parisi A, Eccher A, Barbezeni G, Franchini Z, Iannucci A. Flat epithelial atypia on core needle biopsy: which is the right management? Am J Surg Pathol. 2009;33(7):1078-1084.
    • Martel M, Barron-Rodriguez P, Tolgay Ocal I, Dotto J, Tavassoli FA. Flat DIN 1 (flat epithelial atypia) on core needle biopsy: 63 cases identified retrospectively among 1,751 core biopsies performed over an 8-year period (1992-1999). Virchow’s Arch. 2007;451(5):883-891.
    • Lamb LR, Bahl M, Gadd MA, Lehman CD. Flat epithelial atypia: upgrade rates and risk-stratification approach to support informed decision making. J Am Coll Surg. 2017;225(6):696-701.

Published by Rodrigo Arrangoiz MS, MD, FACS, FSSO

My name is Rodrigo Arrangoiz I am a breast surgeon/ thyroid surgeon / parathyroid surgeon / head and neck surgeon / surgical oncologist that works at Center for Advanced Surgical Oncology in Miami, Florida. I was trained as a surgeon at Michigan State University from (2005 to 2010) where I was a chief resident in 2010. My surgical oncology and head and neck training was performed at the Fox Chase Cancer Center in Philadelphia from 2010 to 2012. At the same time I underwent a masters in science (Clinical research for health professionals) at the University of Drexel. Through the International Federation of Head and Neck Societies / Memorial Sloan Kettering Cancer Center I performed a two year head and neck surgery and oncology / endocrine fellowship that ended in 2016. Mi nombre es Rodrigo Arrangoiz, soy cirujano oncólogo / cirujano de tumores de cabeza y cuello / cirujano endocrino que trabaja Center for Advanced Surgical Oncology en Miami, Florida. Fui entrenado como cirujano en Michigan State University (2005 a 2010 ) donde fui jefe de residentes en 2010. Mi formación en oncología quirúrgica y e n tumores de cabeza y cuello se realizó en el Fox Chase Cancer Center en Filadelfia de 2010 a 2012. Al mismo tiempo, me sometí a una maestría en ciencias (investigación clínica para profesionales de la salud) en la Universidad de Drexel. A través de la Federación Internacional de Sociedades de Cabeza y Cuello / Memorial Sloan Kettering Cancer Center realicé una sub especialidad en cirugía de cabeza y cuello / cirugia endocrina de dos años que terminó en 2016.

Leave a Reply

Fill in your details below or click an icon to log in:

Gravatar
WordPress.com Logo

You are commenting using your WordPress.com account. ( Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. ( Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. ( Log Out /  Change )

Cancel

Connecting to %s