Breast Hamartoma

Rodrigo Arrangoiz MS, MD, FACS, FSSO
Pathologic sections of a 3 cm circumscribed mass. Arrow shows the thin capsule.
  • Histologic section shows non-atypical breast ducts and lobules scattered amongst fibrofatty stroma:
    • With a circumscribed border (arrow shows thin capsule):
      • These features are characteristic of mammary hamartoma:
        • Alternately termed:
        • Fibroadenolipoma
          • Adenolipoma)
  • Hamartomas:
    • Are characterized by normal breast elements in disordered distribution:
      • May harbor other benign findings such as:
        • Pseudoangiomatous stromal hyperplasia (PASH)
        • Apocrine metaplasia
    • The so-called “myoid hamartoma” includes”:
      • Smooth muscle
    • It may be very difficult to recognize and diagnose mammary hamartomas on core biopsy, given the normal constituents:
      • Yet the radiologic appearance of hamartoma is characteristic and is said to resemble “breast within breast”
(a) and (b) – Digital mammograms, medio-lateral oblique (MLO) and cranio-caudad (CC) projections of the right breast showing an large ovoid, encapsulated mass lesion with a ‘breast ] within a breast’ appearance. 
  • Hamartomas are benign breast lesions
  • References:
    • Schnitt SJ, Collins L. Biopsy Interpretation of the Breast. 3rd edition. Philadelphia, PA: Wolters Kluwer, 2018:196-198.
    • Tan PH, Tse G, Lee A, et al. Fibroepithelial tumours. In: Lakhani SR, Ellis IO, Schnit SJ, Tan PH, van de Vijver MJ. eds. WHO Classification of Tumours of the Breast. Lyon: IARC Press, 2012: 147.
    • Tse GM, Tan PH, Lui PC, Putti TC. Spindle cell lesions of the breast–the pathologic differential diagnosis. Breast Cancer Res Treat. 2008;109(2):199-207.
    • Amir RA, Sheikh SS. Breast hamartoma: a report of 14 cases of an under-recognized and under-reported entity. Int J Surg Case Rep. 2016;22:1-4.

Published by Rodrigo Arrangoiz MS, MD, FACS, FSSO

My name is Rodrigo Arrangoiz I am a breast surgeon/ thyroid surgeon / parathyroid surgeon / head and neck surgeon / surgical oncologist that works at Center for Advanced Surgical Oncology in Miami, Florida. I was trained as a surgeon at Michigan State University from (2005 to 2010) where I was a chief resident in 2010. My surgical oncology and head and neck training was performed at the Fox Chase Cancer Center in Philadelphia from 2010 to 2012. At the same time I underwent a masters in science (Clinical research for health professionals) at the University of Drexel. Through the International Federation of Head and Neck Societies / Memorial Sloan Kettering Cancer Center I performed a two year head and neck surgery and oncology / endocrine fellowship that ended in 2016. Mi nombre es Rodrigo Arrangoiz, soy cirujano oncólogo / cirujano de tumores de cabeza y cuello / cirujano endocrino que trabaja Center for Advanced Surgical Oncology en Miami, Florida. Fui entrenado como cirujano en Michigan State University (2005 a 2010 ) donde fui jefe de residentes en 2010. Mi formación en oncología quirúrgica y e n tumores de cabeza y cuello se realizó en el Fox Chase Cancer Center en Filadelfia de 2010 a 2012. Al mismo tiempo, me sometí a una maestría en ciencias (investigación clínica para profesionales de la salud) en la Universidad de Drexel. A través de la Federación Internacional de Sociedades de Cabeza y Cuello / Memorial Sloan Kettering Cancer Center realicé una sub especialidad en cirugía de cabeza y cuello / cirugia endocrina de dos años que terminó en 2016.

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