Medullary Thyroid Carcinoma Pathology

Fine-needle aspirate with immunostaining for calcitonin in medullary cancer of the thyroid. The nuclei of the tumor cells are placed eccentrically and are larger and more pleomorphic than those of normal follicular cells. Immunocytologic staining for calcitonin is positive (brown staining, which is best seen at the arrow). The background contains many red cells that nonspecifically take up the stain.

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