Parathyroid Hormone Receptor

👉Parathyroid hormone (PTH) and PTH-related peptide (PTHrP) both bind and activate one receptor, the G protein-coupled PTH/PTHrP receptor, yet they fulfill very different biological functions – Dr. Rodrigo Arrangoiz

👉PTH is primarily produced in the parathyroid chief cells and is the major regulator of serum calcium.

👉When the level of blood calcium falls, PTH is released from the parathyroid glands and then functions to increase the level of blood calcium.

👉When the level of blood calcium rises, PTH secretion is suppressed.

👉This classic endocrine feedback loop stabilizes the level of blood calcium within a narrow range.

👉PTHrP, by contrast, is expressed in most tissues of the human body and acts locally as a paracrine/autocrine factor.

👉During fetal development and during lactation, PTHrP also acts as a hormone regulating calcium homeostasis.

👉Para más información: http://www.hiperparatiroidismo.info

#Arrangoiz #ParathyroidExpert #ParathyroidSurgeon #Hiperparatiroidism #Hipercalcemia #HeadandNeckSurgeon #SociedadQuirurgica #Hiperparatiroidismo #ExpertoenParatiroides #CirujanodeParatiroides

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s