Common Sites of Metastatic Disease from Nasopharyngeal Carcinoma (NPC)

  • Frequencies of metastases from NPC were as follows:
    • Bone:
      • 75% of the cases
    • Lung:
      • 46% of the cases
    • Liver:
      • 38% of the cases
    • Retroperitoneal lymph nodes:
      • 10% of the cases
    • Multiple organ involvement:
      • Is as high as:
        • 57% of the cases
  • Most of the distant metastases (95%):
    • Occurred within three years:
      • After completion of radiotherapy:
        • The first year:
          • 52%
        • The second year:
          • 23%
        • The third year:
          • 20%
  • The median survival time from the discovery of distant metastasis is :
    • 11.2 months:
      • For bone metastasis
    • 16.3 months:
      • For pulmonary metastasis
    • 3.2 months:
      • For hepatic metastasis

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