T Staging of Oral Pharyngeal Squamous Cell Carcinoma (OPSCC) Human Papilloma Virus (HPV) Negative

Rodrigo Arrangoiz MS, MD, FACS, FSSO
  • NCCN Guidelines, Head and Neck Cancers (v2.2026) still base clinical staging definitions on AJCC 8th edition (ST-4 for p16-negative, ST-7 for p16-positive):
    • Version 9 is not yet incorporated
  • Version 9 changes apply only to:
    • HPV-positive (p16+) oropharyngeal carcinoma
  • The p16-negative oropharynx / hypopharynx system:
    • Is unchanged in the current NCCN tables
  • T – Tumor:
    • TX – Primary tumor cannot be assessed
    • Tis – Carcinoma in situ
    • T1 – Tumor 2 cm or smaller in greatest dimension
    • T2 – Tumor larger than 2 cm but not larger than 4 cm in greatest dimension
    • T3 – Tumor larger than 4 cm in greatest dimensión or extensión to lingual surface of epiglottis
    • T4 – Moderately advanced or very advanced local disease
      • T4a – Moderately advanced local disease
        • Tumor invades the larynx, extrinsic muscle of tongue, medial pterygoid muscle, hard palate, or mandible
      • T4b – Very advanced local disease
        • Tumor invades lateral pterygoid muscle, pterygoid plates, lateral nasopharynx, or skull base or encases carotid artery
#Arrangoiz #HeadandNeckSurgeon #CancerSurgeon #SurgicalOncology #OropharyngealCancer #Teacher #Surgeon #MountSinaiMedicalCenter #MSMC #BramanComprehensiveCancerCenter #BCCC #Miami #Mexico
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Published by Rodrigo Arrangoiz MS, MD, FACS, FSSO

My name is Rodrigo Arrangoiz I am a breast surgeon/ thyroid surgeon / parathyroid surgeon / head and neck surgeon / surgical oncologist that works at Center for Advanced Surgical Oncology in Miami, Florida. I was trained as a surgeon at Michigan State University from (2005 to 2010) where I was a chief resident in 2010. My surgical oncology and head and neck training was performed at the Fox Chase Cancer Center in Philadelphia from 2010 to 2012. At the same time I underwent a masters in science (Clinical research for health professionals) at the University of Drexel. Through the International Federation of Head and Neck Societies / Memorial Sloan Kettering Cancer Center I performed a two year head and neck surgery and oncology / endocrine fellowship that ended in 2016. Mi nombre es Rodrigo Arrangoiz, soy cirujano oncólogo / cirujano de tumores de cabeza y cuello / cirujano endocrino que trabaja Center for Advanced Surgical Oncology en Miami, Florida. Fui entrenado como cirujano en Michigan State University (2005 a 2010 ) donde fui jefe de residentes en 2010. Mi formación en oncología quirúrgica y e n tumores de cabeza y cuello se realizó en el Fox Chase Cancer Center en Filadelfia de 2010 a 2012. Al mismo tiempo, me sometí a una maestría en ciencias (investigación clínica para profesionales de la salud) en la Universidad de Drexel. A través de la Federación Internacional de Sociedades de Cabeza y Cuello / Memorial Sloan Kettering Cancer Center realicé una sub especialidad en cirugía de cabeza y cuello / cirugia endocrina de dos años que terminó en 2016.

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