Expanded Role of BRCA Testing and Adjuvant PARP Inhibition in Early Breast Cancer

  • In the OlympiA trial:
    • Adjuvant therapy with olaparib vs placebo demonstrated a benefit in overall survival, invasive disease‒free survival, and distant disease‒free survival in eligible patients with early breast cancer and gBRCApathogenic variants.
  • With the expanded role of BRCA testing in early breast cancer, completion of testing in eligible patients is critical
  • Given the survival benefit of adjuvant PARP inhibition in this population:
    • Patient and healthcare professional education on the importance of genetic testing and benefits of therapy is key
#Arrangoiz #BreastSurgeon #Surgeon #SurgicalOncologist #BRCAMutation #MountSinaiMedicalCenter #MSMC #Miami #Mexico

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