How to Evaluate a Breast Nodule on Ultrasound of the Breast?

  • You first evaluate the lesion for:
    • Any of the 10 malignant signs:
      • Shadowing
      • Hypoechoic echotexture
      • Spiculation
      • Angular margins
      • Thick echogenic halo
      • Microlobulation
      • Taller than wide
      • Duct extension
      • Branching pattern
    • Calcifications
  • Finding none:
    • You move on to the second step in the evaluation process:
      • Specifically look for one of the 3 strictly defined benign signs:
        • If any of them are found:
          • The lesion can be considered BIRADS 3:
            • A 6-month follow-up ultrasound would be appropriate unless the anxiety of the patient makes core biopsy a better option
    • The 3 benign findings defined by Stavros are:
      • A purely hyperechoic lesion:
        • With no hypoechoic area larger than a normal duct or lobule
      • Elliptical, wider than tall, well-circumscribed and thin echogenic capsule
      • Gently lobulated, wider than tall, well-circumscribed and thin echogenic capsule
      • Combining the elliptical or gently lobulated shapes:
        • With the presence of a complete, thin echogenic capsule:
          • Is necessary because many circumscribed carcinomas and most ductal carcinoma in situ are encompassed in a thin, echogenic capsule:
            • However, the shape of circumscribed invasive carcinoma or pure ductal carcinoma in situ:
              • Is rarely elliptical or gently lobulated:
  • References:
    • Madjar H, Mendelson EB. The Practice of Breast Ultrasound. 2nd ed. Thieme; 2008;141-144.
    • Stavros AT. Breast Ultrasound. Philadelphia, PA: Lippincott Williams & Wilkins; 2004.
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