Male Breast Cancer on Imaging

  • The mammogram shows a spiculated mass with extensive edema:
    • As evidenced by skin thickening and increased trabecular markings in the breast (Images)
  • Ultrasound shows a heterogeneous, irregular, hypoechoic mass with some angular and spiculated margins (Image):
    • Internal vascularity is demonstrated on Doppler examination (Image)
  • Gynecomastia:
    • Does not cause erythema, skin thickening, and breast edema:
      • The mammogram would usually show a triangular shaped density radiating from the nipple into the breast tissue (Image)
Classic mammographic image of gynecomastia
  • The sides of the mammographic triangle in gynecomastia are:
    • Usually straight or concave (Image) as opposed to convex in breast cancer
  • The sonographic appearance of gynecomastia depends on the phase of development:
    • It can appear quite hypoechoic and have angular margin
  • Paget’s disease of the breast is rare, but it does occur in males:
    • It would present with a nipple rash and would not be expected to have secondary infection
    • There are usually no mammographic or sonographic features unless there is an underlying invasive carcinoma
  • References
    • Abeywardhana DY, Nascimento VC, Dissanayake D, Taylor D, Metcalf C, Saunders C, et al. Review of ultrasound appearance in inflammatory breast cancer: a pictorial essay. J Med Imaging Radiat Oncol. 2016;60(1):83-87.
    • Stavros AT. Evaluation of the male breast. In: Stavros AT. Breast Ultrasound. Philadelphia, PA: Lippincott Williams & Wilkins; 2004:712-741.
    • Khalkhali I, Cho J. Male breast cancer imaging. Breast J. 2015;21(3):217-218.
    • Ottini L, Palli D, Rizzo S, Ferico M, Bazan V, Russo A. Male breast cancer. Crit Rev Oncol Hematol. 2010;73(2):141-155.
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