Prophylactic Mastectomy

  • Current consensus guidelines from the American Society of Breast Surgeons:
    • Do not recommend contra lateral prophylactic mastectomy (CPM):
      • For women with sporadic breast cancers
  • A Cochrane review of eight studies evaluating patients who underwent CPM concluded that:
    • While CPM reduces risk of contralateral breast cancer:
      • It is not associated with improved survival
  • Reasons for not recommending CPM include:
    • A low estimated risk of cancer in the contralateral breast:
      • 2% to 6% over 10 years
    • Increased complication rates
    • Studies showing that CPM does not improve survival or recurrence from the index cancer


Lostumbo L, Carbine N, Wallace J, Ko H. Prophylactic mastectomy for the prevention of breast cancer. Cochrane Database Syst Rev 2004(4):CD002748.

Boughey JC, Attai DJ, Chen SL, et al. Contralateral prophylactic mastectomy consensus statement from the american society of breast surgeons: additional considerations and a framework for shared decision making. Ann Surg Oncol. 2016;23(10):3106-3111.

#Arrangoiz #BreastSurgeon #CancerSurgeon #SurgicalOncologist #Miami #Mexico #BreastCancer #ProphylacticMastectomy #MountSinaiMedicalCenter #MSMC

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