Clinical Presentation of Floor of the Mouth Tumors

  • Since the floor of mouth is a relatively small anatomical area:
    • Tumors frequently extend into adjacent sites notably the tongue or mandible
  • Patients may present with a:
    • Sore lesion
    • Ulceration
    • Obstructive submandibular gland symptoms
  • Leukoplakia of the floor of mouth:
    • May be considered a pre-malignant condition with an annual transformation rate of 1% to 2.9%:
      • The demonstration of carcinoma within an excised leukoplakia not being uncommon
  • Stage at presentation varies considerably between institutions:
    • Although approximately 50% present with advanced disease
  • Cervical lymphadenopathy is present in 17% to 45% of patients on presentation:
    • Up to 22% of those clinically N0 at presentation having occult metastasis
    • Depending on the location of the tumor:
      • Up to 28.6% of patients may have bilateral nodal involvement
  • Many tumors of the floor of mouth are well or moderately differentiated
#Arrangoiz #MountSinaiMedicalCenter #CancerSurgeon #SurgicalOncologist #HeadandNeckSurgeon #Miami #Mexico

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