Laboratory Test in Hyperparathyroidism

👉Common labs ordered in the workup of patients with Primary hyperparathyroidism include a serum calcium (+/- ionized calcium), albumin (for correction of total serum calcium level), PTH, phosphate, creatinine, 25-hydroxy vitamin D, and a 24-hour urine calcium & creatinine.

👉Hypercalcemia with with an elevated PTH with normal kidney function and without hypocalciuria indicates primary hyperparathyroidism.

👉However, some patients with this disease will have hypercalcemia with an “inappropriately normal” PTH – this can be a common cause of delayed diagnosis.

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