Contralateral Prophylactic Mastectomy (CPM)

  • Current consensus guidelines from the American Society of Breast Surgeons:
    • Do not recommend CPM for women with sporadic breast cancers
  • A Cochrane review of eight studies evaluating patients who underwent CPM:
    • Concluded that while CPM reduces risk of contralateral breast cancer:
      • It is not associated with improved survival
  • Reasons for not recommending CPM include:
    • A low estimated risk of cancer in the contralateral breast:
      • 2% to 6% over 10 years)
    • Increased complication rates
    • Studies showing that CPM does not improve survival or recurrence from the index cancer
  • References
  • Lostumbo L, Carbine N, Wallace J, Ko H. Prophylactic mastectomy for the prevention of breast cancer. Cochrane Database Syst Rev 2004(4):CD002748.
  • Boughey JC, Attai DJ, Chen SL, et al. Contralateral prophylactic mastectomy consensus statement from the american society of breast surgeons: additional considerations and a framework for shared decision making. Ann Surg Oncol. 2016;23(10):3106-3111.

#Arrangoiz #CASO #CenterforAdvancedSurgicalOncology #BreastSurgeon #CancerSurgeon #SurgicalOncology #BreastCancer

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