What where the surgical side effect of sentinel lymph node dissection as reported by the American College of Surgeons Oncology Group (ACOSOG) Z0010 trial?

  • The overall significant complication rate from sentinel lymph node dissection:
    • Reported from the ACOSOG Z0010 trial:
      • Was low:
        • With 32% of patients:
          • Reporting at least one surgical side effect:
            • Less than 1% of patients:
              • Requiring hospitalization
    • The most common surgical side effect:
      • Was axillary paresthesias:
        • Affecting 307 (8.6%) of 3573 patients
    • Allergic reaction:
      • Was reported in less than 1% of the cases
      • There was only one:
        • Anaphylactic reaction reported
    • Lymphedema:
      • Was reported in 7% of the cases
    • Brachial plexus injury:
      • Was reported in less than 1% of patients


  1. Hunt KK, Ballman KV, McCall LM, et al. Factors associated with local-regional recurrence after a negative sentinel node dissection: results of the ACOSOG Z0010 trial. Ann Surg. 2012;256:428-436.
  2. Boughey JC, Hunt KK. The ACOSOG experience. In: Kuerer HM, ed. Kuerer’s Breast Surgical Oncology. New York, NY: McGraw-Hill Companies; 2010:517-530.

#Arrangoiz #BreastSurgeon #BreastCancer #CancerSurgeon #SurgicalOncologist

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