- Carcinoid tumors are classically defined as:
- Well-differentiated:
- Low- to intermediate-grade neuroendocrine tumors:
- Traditionally:
- High-grade or poorly differentiated neuroendocrine tumors are classified as:
- Neuroendocrine carcinomas:
- Although many refer to any small bowel neuroendocrine tumor as:
- A carcinoid tumor:
- Which is the term I favor
- A carcinoid tumor:
- Although many refer to any small bowel neuroendocrine tumor as:
- Neuroendocrine carcinomas:
- High-grade or poorly differentiated neuroendocrine tumors are classified as:
- Traditionally:
- Low- to intermediate-grade neuroendocrine tumors:
- Well-differentiated:
- Carcinoid tumors:
- Arise most commonly from:
- The gastrointestinal (GI) tract:
- But can also arise in the:
- Lungs
- Other rare additional sites:
- Such as the genitourinary system
- But can also arise in the:
- The gastrointestinal (GI) tract:
- Within the GI tract:
- Carcinoid tumors most commonly arise from the:
- Small bowel (45%)
- Rectum (20%)
- Appendix (17%):
- This data is based on a Survival, Epidemiology, and End Results (SEER) database report from 1973 to 1997:
- Although rectal carcinoids are becoming more common:
- Since the advent of screening colonoscopy
- Although rectal carcinoids are becoming more common:
- This data is based on a Survival, Epidemiology, and End Results (SEER) database report from 1973 to 1997:
- Carcinoid tumors most commonly arise from the:
- Epidemiology:
- The annual incidence of newly diagnosed small bowel carcinoid tumors:
- Is 9.3 per million:
- Although the true incidence may be higher based on postmortem studies
- Is 9.3 per million:
- However, the significance of early-stage and extremely low-grade preclinical carcinoid tumors is:
- Unknown
- Carcinoid tumors are:
- The most common small bowel malignancies:
- Slightly more common than adenocarcinomas:
- 37.4% versus 36.9%
- Slightly more common than adenocarcinomas:
- Their incidence has been rising by:
- An average of 3.6% annually:
- Over the past 30 years
- An average of 3.6% annually:
- The most common small bowel malignancies:
- They are slightly more common in men than in women:
- 52% versus 48%
- Te median age at diagnosis is:
- 66
- The annual incidence of newly diagnosed small bowel carcinoid tumors:
- Arise most commonly from:

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