What is the best imaging modality to determine imaging response to neoadjuvant therapy in breast cancer?

👉Breast MRI is the most sensitive and specific imaging modality to determine imaging response to neoadjuvant therapy and has the highest correlation coefficient when comparing imaging size to pathologic tumor size when compared to any combination of physical examination, mammography, and ultrasonography.
👉Nevertheless, it is not necessary to routinely perform post-treatment MRI, especially when a well-circumscribed sonographically visible cancer has been followed with ultrasound during treatment.
👉Researchers are studying breast specific gama imaging (BSGI) as an enhanced screening modality but its accuracy in determining tumor detection and response after neoadjuvant therapy is unproven. The high dose of radiation with BSGI has been a concern. 


  1. De Los Santos JF, Cantor A, Amos KD, et al. Magnetic resonance imaging as a predictor of pathologic response in patients treated with neoadjuvant systemic treatment for operable breast cancer (TBCRC 017). Cancer. 2013;199:1776-1783.
  2. Lee HS, Ko BS, Ahn SH, et al. Diagnostic performance of breast-specific gamma imaging in the assessment of residual tumor after neoadjuvant therapy in breast cancer patients. Breast Cancer Res Treat. 2014;145:91-100.
  3. Marinovich ML, Macaskill P, Irwig L, et al. Meta-analysis of agreement between MRI and pathologic breast tumour size after neoadjuvant chemotherapy. Br J Cancer. 2013; 109:1528-1536.
  4. McLaughlin S, Mittendorf EA, Bleicher RJ, et al. The 2013 Society of Surgical Oncology Susan G. Komen for the Cure Symposium: MRI in breast cancer: where are we now? Ann Surg Oncol. 2014;21:28-36.

👉Rodrigo Arrangoiz MS, MD, FACS cirujano oncology y cirujano de mamá de Sociedad QuirĂşrgica S.C en el America British Cowdray Medical Center en la ciudad de Mexico:

  • Es experto en el manejo del cáncer de mama.


👉Es miembro de la American Society of Breast Surgeons:


• General surgery:

• Michigan State University:

• 2004 al 2010

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• Fox Chase Cancer Center (Filadelfia):

• 2010 al 2012

• Masters in Science (Clinical research for health professionals):

• Drexel University (Filadelfia):

• 2010 al 2012

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• IFHNOS / Memorial Sloan Kettering Cancer Center:

• 2014 al 2016











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