Thyroid Awareness Month – Papillary Thyroid Cancer (PTC) – The Most Common Subtype

Papillary thyroid cancer (PTC) accounts for ~80–85% of all thyroid cancers. It is also the subtype with the best overall prognosis.

🧠 Key characteristics of PTC

Typically slow-growing Often diagnosed at an early stage May spread to neck lymph nodes, especially in younger patients Even with lymph node involvement, long-term survival remains excellent

🔍 How is PTC usually detected?

Incidentally on high-resolution ultrasound Confirmed with ultrasound-guided FNA biopsy Often small tumors (≤2 cm) at diagnosis

⚖️ How is papillary thyroid cancer treated?

Treatment is risk-adapted and may include:

Active surveillance for selected very low-risk tumors Thyroid lobectomy for low-risk disease Total thyroidectomy for higher-risk cases Selective lymph node surgery when indicated Radioactive iodine only for patients who truly benefit

➡️ Not all patients need the same treatment.

📈 Prognosis

10-year survival >95% Many patients live normal lifespans Focus is increasingly on quality of life, not just cure

👨‍⚕️ Dr. Rodrigo Arrangoiz, MD

Surgical Oncologist – Thyroid, Head & Neck, Breast

Mount Sinai Medical Center

📌 Take-home message:

Papillary thyroid cancer is common, highly treatable, and often requires less aggressive treatment than patients expect.

📚 References

Haugen BR et al. ATA Guidelines for Differentiated Thyroid Cancer. Thyroid Tuttle RM et al. Risk-adapted management of papillary thyroid cancer. Lancet Diabetes Endocrinol SEER Cancer Statistics Review

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