Breast Cancer Chest Wall Recurrence Management

  • Patients with chest wall recurrence:
    • Are at high risk for concurrent systemic recurrences:
      • Therefore, obtaining systemic staging and receptor information on the recurrence should be the first consideration
    • Often, there may be extensive local regional involvement in several areas along the chest wall and in the nodal regions
  • According to National Comprehensive Cancer Network guidelines:
    • Systemic staging generally consists of either a:
      • PET/ CT scan or a CT of the chest, abdomen, and pelvis, as well as a bone scan
  • Surgical excision with negative margins followed by comprehensive chest wall and nodal radiotherapy:
    • May be indicated in the absence of widespread systemic disease
  • This patient should be managed by a multidisciplinary team:
    • Including the surgeon, medical oncologists, radiologists, pathologists, and potentially a plastic surgeon
  • Patients may or may not benefit from chemotherapy:
    • In the CALOR trial:
      • Chemotherapy was found to benefit patients with resected ER negative isolated locoregional recurrence:
        • But not ER positive isolated local regional recurrence
  • References

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