Breast Cancer Recurrence after Mastectomy

  • The main goal of routine post-treatment follow-up is:
    • The early detection of local-regional recurrence
  • For patients with locally recurrent breast cancer, that appears to be confined to the soft tissue of the chest wall, and no evidence of metastatic disease:
    • When possible, surgical resection of the tumor is the initial treatment of choice for most patients
  • Following surgery:
    • The addition of radiation therapy appears to further decrease the risk of a subsequent local recurrence
  • The addition of adjuvant systemic therapy:
    • Should be considered for patients who suffer local recurrence with more than minimal tumor burden
  • References:
    • Aebi S, Wapnir I. Management of locoregional recurrences. In: Winchester D J, Winchester D P, Hudis C A, and Norton L eds. Breast Cancer 2nd ed. Hamilton, Canada: B C Deker, Inc; 2006:511-523.
    • Buchanan C L, Dorn P L, Fey J, et al. Locoregional recurrence after mastectomy: incidence and outcomes. J Am Coll of Surg. 2006;203:469-474.
    • Dahlstrøm K K, Andersson A P, Andersen M, Krag C. Wide local excision of recurrent breast cancer in the thoracic wall. Cancer. 1993;72:774-777.
    • National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology. Breast Cancer. Available at http://www.nccn.org.

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