Management of the Wound After Melanoma Resection

  • Wound Closure:
    • If there is concern regarding the ability to achieve suitable wound closure:
      • A plastic or reconstructive surgeon may be consulted:
        • Ideally in the preoperative setting
  • Options for closure include:
    • Primary closure
    • Skin grafting
    • Local and distant flaps
  • Primary closure:
    • Is the method of choice for most lesions:
      • But it should be avoided when it will distort the appearance of a mobile facial feature or interfere with function
    • Many defects can be closed using an advancement flap, undermining the skin and subcutaneous tissues to permit primary closure
    • Primary closure may be facilitated with the longitudinal axis of an elliptical incision to be approximately three times the length of the short axis:
      • Lesser extension of the longitudinal axis can also sometimes be employed
    • The skin and subcutaneous tissue are removed down to, but generally not including the underlying muscular fascia
    • Closure of the wound edges is usually performed in two layers:
      • A dermal layer of 3-0 undyed absorbable sutures and either interrupted skin closure using 2-0, 3-0, or 4-0 nonabsorbable sutures and / or a running subcuticular skin closure using 4-0 monofilament absorbable sutures
    • Three layers are sometimes used:
      • Particularly for primary melanomas of the back:
        • With approximation of Scarpa’s fascia
    • After excision:
      • The specimen should be oriented for permanent assessment of histologic margins
  • Application of a skin graft is one of the simplest reconstructive methods used for wound closure:
    • Split-thickness skin grafts are most commonly used:
      • For lower extremity primary lesions:
        • Split-thickness grafts can be harvested from the contralateral extremity
    • In general, skin grafts should be harvested from an area remote from the primary melanoma and outside the zone of potential in-transit metastasis
    • A full-thickness skin graft:
      • Can provide a result that is both more durable and of higher aesthetic quality than a split-thickness graft
      • Full-thickness grafts have most commonly been used on the face:
        • Where aesthetic considerations are most significant, but can also be used elsewhere
      • Donor sites for full-thickness skin graft to the face:
        • Should be chosen from locations that are likely to match the color of the face:
          • Such as the postauricular or preauricular skin or the supraclavicular portion of the neck
      • Local flaps:
        • Offer numerous advantages for repair of defects that cannot be closed primarily:
          • Especially on the distal extremities and on the head and neck
        • Color match is excellent, durability of the skin is essentially normal, and normal sensation is usually preserved
      • Transposition flaps and rotation flaps of many varieties have been used:
        • Although for patients with high risk of in-transit metastasis, extensive flap reconstruction may significantly alter regional lymphatics
      • Distant flaps may be considered when sufficient tissue for a local flap is not available and when a skin graft would not provide adequate wound coverage
      • Use of a wound VAC to facilitate granulation tissue:
        • That serves as a healthy tissue bed for subsequent skin graft can often obviate the need for complex reconstructive options (e.g., melanoma arising on the heel of the foot)

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