Hashimoto’s Thyroiditis (Chronic Lymphocytic Thyroidits)

Rodrigo Arrangoiz MS, MD, FACS, FSSO
  • Of all autoimmune disorders, chronic lymphocytic thyroiditis, also known as Hashimoto’s thyroiditis:
    • Is by far the most prevalent
  • The eponym Hashimoto’s thyroiditis (HT):
    • Relates to Dr. Hashimoto, from Japan, who, in 1912:
      • First reported a connection between goiter and intrathyroidal lymphocytic inflammation:
        • Referring to it as“struma lym-
          phomatosa”
  • HT is understood to be an autoimmune condition:
    • In which activation of the immune system against the thyroid:
      • Leads to increased presentation of thyroid antigens and a rise in Th-1 T-cell cytotoxic action:
        • Mediated by ICAM-1-mediated CD8+ cells:
          • Thereby causing the disruption of thyroid follicles and cell apoptosis
  • Typically, thyroid peroxidase antibodies (TPOAb) and / or thyroglobulin antibodies (TgAb):
    • Can be measured in the serum of patients with active HT
  • In the general population, up to 20% of adults may have measurable thyroid antibody titers, which occur more often in the elderly and women
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Published by Rodrigo Arrangoiz MS, MD, FACS, FSSO

My name is Rodrigo Arrangoiz I am a breast surgeon/ thyroid surgeon / parathyroid surgeon / head and neck surgeon / surgical oncologist that works at Center for Advanced Surgical Oncology in Miami, Florida. I was trained as a surgeon at Michigan State University from (2005 to 2010) where I was a chief resident in 2010. My surgical oncology and head and neck training was performed at the Fox Chase Cancer Center in Philadelphia from 2010 to 2012. At the same time I underwent a masters in science (Clinical research for health professionals) at the University of Drexel. Through the International Federation of Head and Neck Societies / Memorial Sloan Kettering Cancer Center I performed a two year head and neck surgery and oncology / endocrine fellowship that ended in 2016. Mi nombre es Rodrigo Arrangoiz, soy cirujano oncólogo / cirujano de tumores de cabeza y cuello / cirujano endocrino que trabaja Center for Advanced Surgical Oncology en Miami, Florida. Fui entrenado como cirujano en Michigan State University (2005 a 2010 ) donde fui jefe de residentes en 2010. Mi formación en oncología quirúrgica y e n tumores de cabeza y cuello se realizó en el Fox Chase Cancer Center en Filadelfia de 2010 a 2012. Al mismo tiempo, me sometí a una maestría en ciencias (investigación clínica para profesionales de la salud) en la Universidad de Drexel. A través de la Federación Internacional de Sociedades de Cabeza y Cuello / Memorial Sloan Kettering Cancer Center realicé una sub especialidad en cirugía de cabeza y cuello / cirugia endocrina de dos años que terminó en 2016.

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