Lymph Node Dissection in Thyroid Cancer

  • Papillary thyroid cancer (PTC):
    • Has a high predilection for spread to locoregional lymph nodes (LNs):
      • Occurring in up to 40% to 90% of cases:
        • When prophylactic nodal dissection is performed:
        • Though such high rates of metastatic disease may prove enticing to recommend routine prophylactic node dissection:
          • Recurrence-free survival is not effected by the removal of sonographically normal, microscopically diseased nodes
        • Instead, prophylactic central neck dissection may be individually considered for those patients with:
          • T3 or T4 tumors, or in the presence of lateral neck metastases
        • Clinically suspicious or biopsy-proven nodal disease warrants a “therapeutic” dissection of the involved compartments
          • “Berry picking,” or selective removal of suspicious LN metastases, is not recommended:
            • As it is associated with significantly higher recurrence rates and does not lower the rate of postoperative complications compared with systematic compartmental dissections
  • The risk of surgical complications with nodal dissection should be weighed against the benefit of LN removal:
    • Central neck dissections may result in temporary or permanent injury to the RLN and hypoparathyroidism
    • Surgeon case volume predicts patient outcomes:
      • Those performing less than 10 cases compared with those performing more than 100 cases per year had complications in 24% and 14.5% of cases, respectively
    • Although dissection of the lateral neck is less often associated with adverse events:
      • Injury to the spinal accessory nerve may occur with dissection of level II or V
    • Similarly, chyle leaks may be seen after removal of nodes in level IV:
      • Particularly on the left side
#Arrangoiz #Surgeon #Doctor #Surgeon #CancerSurgeon #ThyroidSurgeon #ParathyroidSurgeon #HeadandNeckSurgeon #SurgicalOncologist #Miami #Mexico #MountSinaiMedicalCenter #MSMC #ThyroidCancer

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