Invasive Encapsulated Follicular Variant of Papillary Thyroid Carcinoma (IEFVPTC)

Rodrigo Arrangoiz MS, MD, FACS, FSSO
  • Invasive encapsulated follicular variant of papillary thyroid carcinoma (IEFVPTC):
    • Is now considered a separate entity and no longer a subtype of PTC
  • IEFVPTC has a RAS-like mutational and transcriptomic profile:
    • Similar to that of follicular adenoma (FA) and follicular thyroid carcinoma (FTC) (Figure):
      • Whereas classic PTC and the infiltrative follicular subtype of PTC:
        • Have BRAF V600E-like molecular profiles
  • IEFVPTCs:
    • Have a fibrous capsule or well-defined border and lack the histologic features of infiltrative follicular PTC
  • Like FTC:
    • IEFVPTC can invade vessels in the capsule and develop distant metastasis
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Published by Rodrigo Arrangoiz MS, MD, FACS, FSSO

My name is Rodrigo Arrangoiz I am a breast surgeon/ thyroid surgeon / parathyroid surgeon / head and neck surgeon / surgical oncologist that works at Center for Advanced Surgical Oncology in Miami, Florida. I was trained as a surgeon at Michigan State University from (2005 to 2010) where I was a chief resident in 2010. My surgical oncology and head and neck training was performed at the Fox Chase Cancer Center in Philadelphia from 2010 to 2012. At the same time I underwent a masters in science (Clinical research for health professionals) at the University of Drexel. Through the International Federation of Head and Neck Societies / Memorial Sloan Kettering Cancer Center I performed a two year head and neck surgery and oncology / endocrine fellowship that ended in 2016. Mi nombre es Rodrigo Arrangoiz, soy cirujano oncólogo / cirujano de tumores de cabeza y cuello / cirujano endocrino que trabaja Center for Advanced Surgical Oncology en Miami, Florida. Fui entrenado como cirujano en Michigan State University (2005 a 2010 ) donde fui jefe de residentes en 2010. Mi formación en oncología quirúrgica y e n tumores de cabeza y cuello se realizó en el Fox Chase Cancer Center en Filadelfia de 2010 a 2012. Al mismo tiempo, me sometí a una maestría en ciencias (investigación clínica para profesionales de la salud) en la Universidad de Drexel. A través de la Federación Internacional de Sociedades de Cabeza y Cuello / Memorial Sloan Kettering Cancer Center realicé una sub especialidad en cirugía de cabeza y cuello / cirugia endocrina de dos años que terminó en 2016.

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