Axillary Web Syndrome

  • Axillary web syndrome:
    • Appears to be a common complication following axillary surgery
    • It consists of the appearance of a visible web of axillary skin overlying palpable cords of tissue:
      • That are made taut and painful by shoulder abduction
    • These cords can result in painful abduction of the shoulder and reduced range of motion
    • It typically results from axillary lymphadenectomies for treatment of breast cancer or melanoma
    • In general, axillary web syndrome is poorly defined and misunderstood:
      • In a large systematic review:
        • The incidence ranged from 0.6% to 85.4%
      • Extent of surgery (number of nodes removed), low body mass index, and age have been reported as possible risk factors for development of this syndrome
      • Although smoking, receipt of neoadjuvant chemotherapy, and radiation may play a role in its development:
        • These factors have not been described in the literature
      • In the majority of cases:
        • Axillary web syndrome:
          • Appears to develop within 2 to 8 weeks of axillary surgery
      • Although patients generally do well with resolution of their symptoms:
        • Current evidence for the treatment of axillary web syndrome is insufficient to provide clear guidance for clinical practice
      • Suggested interventions have included:
        • Early education
        • Physiotherapy
        • Thermal therapy
        • Medications
        • Surgery
  • References:
  • Koehler LA, Haddad TC, Hunter DW, Tuttle TM. Axillary web syndrome following breast cancer surgery: symptoms, complications and management strategies. Breast Cancer. 2018;11:13-19.
  • Yeung WM, McPhail SM, Kuys SS. A systematic review of axillary web syndrome (AWS). J Cancer Surviv. 2015;9(4):576-598

Leave a comment