Contralateral Mastectomy (CM) Rates in the USA.

  • In the United States (US), CM rates have been increasing for more than two decades:
    • One study using the Surveillance, Epidemiology, and End Results (SEER) database:
      • Showed that the rates of CM in patients with unilateral breast cancer (UBC) undergoing mastectomy increased:
        • From 4.2% in 1998 to 11.0% in 2003
    • A similar study using the National Cancer Database (NCDB):
      • Showed that the CM rate increased from 0.4% in 1998 to 4.7% in 2007
    • Since then, several other studies have demonstrated a continuation of this trend in the US:
      • Reporting CM rates as high as 30% to 50% in certain patient populations
  • This trend of increasing CM rates has also been seen in patients with ductal carcinoma in situ
  • Factors associated with undergoing CM are:
    • Caucasian race
    • Private insurance
    • Higher socioeconomic status
    • High volume centers
    • Younger age
    • Use of breast MRI
    • Genetic testing
    • Reconstructive surgery
  • Surgeons have also been shown to influence the likelihood of CM:
    • For example, if a surgeon recommends against CM:
      • The likelihood of undergoing CM decreases:
        • In a survey study of patients who underwent definitive surgery for breast cancer:
          • Those whose surgeons recommended against CM had a CM rate of 6.1%:
            • Whereas those who received no recommendation had a CM rate of 57.5
  • Shared decision making has been shown to reduce decision-related conflict and regret

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