Smoking and Obesity have been shown to significantly increase risk of complications in patients undergoing autologous tissue breast reconstruction?

  • Smoking and obesity:
    • Increase the risk of complications for all types of breast reconstruction:
      • Whether with implant or flap
  • Smoking and obesity:
    • Are therefore considered a relative contraindication to breast reconstruction:
      • Patients should be made aware of increased rates of wound healing complications and partial or complete flap failure:
        • Among smokers and obese patients
  • Alcohol intake:
    • Has not been shown to be a significant risk factor for complication with breast reconstruction
  • While age greater than 70 alone has not been shown to increase risk of complication in patients undergoing autologous tissue breast reconstruction:
    • Patients over 70 years may be more likely to have other comorbidities
  • Patients undergoing immediate autologous breast reconstruction following neoadjuvant chemotherapy have a similar complication and reoperation rates to patients not receiving neoadjuvant chemotherapy
  • References
    • National Comprehensive Cancer Network. Breast Cancer (Version 3.2019). https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf. Accessed January 13, 2020.
    • Angarita FA, Dossa F, Zuckerman J, McCready DR, Cil TD. Is immediate breast reconstruction safe in women over 70? An analysis of the National Surgical Quality Improvement Program (NSQIP) database. Breast Cancer Res Treat. 2019;177(1):215-224
    • Beugels J, Meijvogel JLW, Tuinder SMH, Tjan-Heijnen VCG, Heuts EM, Piatkowski A, et al. The influence of neoadjuvant chemotherapy on complications of immediate DIEP flap breast reconstructions. Breast Cancer Res Treat. 2019;176(2):367-375.
    • Schaverien MV, Munnoch DA. Effect of neoadjuvant chemotherapy on outcomes of immediate free autologous breast reconstruction. Eur J Surg Oncol. 2013;39(5):430-436.
    • Hu YY, Weeks CM, In H, Dodgion CM, Golshan M, Chun YS, et al. Impact of neoadjuvant chemotherapy on breast reconstruction. Cancer. 2011;117(13):2833-2841.

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