Simple Breast Cyst

  • Although most of these lesions are benign:
    • The presence of a mass can cause significant anxiety because of the concern that the mass represents a cancer
  • A mass can be solid or cystic and is not always seen on a mammogram
  • An ultrasound of the breast:
    • Can determine whether a breast mass is cystic or solid
  • Cysts are most frequently seen in women who are 40 to 49 years old:
    • But they may be present at any age
  • Cysts are most often hormonally regulated and may occur in the perimenopausal period
  • Cysts on ultrasound:
    • Can be either simple or complex
  • Ultrasound is 90% to 100% accurate for characterization of benign cysts when strict criteria are used
  • Simple cysts:
    • Have a negligible risk of cancer, and current evidence indicates that a simple cyst does not need to aspirated:
      • Unless it is symptomatic, and no other work-up is necessary
  • Simple cysts on ultrasound are:
    • Anechoic, well circumscribed, with smooth walls and posterior enhancement, as depicted in the image
  • Complex cysts:
    • Have a very low malignancy rate (0.3%) and a 6-month follow-up ultrasound is reasonable
    • However, a complex cystic lesion with a significant solid component:
      • May have an associated cancer risk of up to 23%
    • Therefore, if the mass has a solid component:
      • A biopsy is indicated to rule out an associated malignancy
  • References:
    • Berg WA, Campassi CI, Ioffe OB. Cystic lesions of the breast: sonographic-pathologic correlation. Radiology. 2003;227:183-191.
    • Morrow M, Wong S, Vetna L. The evaluation of breast masses in women younger than forty years of age. Surgery. 1998;124:643-640.
    • Osborne MP, Boolbol S, Asad J. Benign conditions of the breast. In Kuerer H (ed.): Breast Surgical Oncology. New York, NY: McGraw-Hill; 2010:165-179.
    • Venta LA, Kim JP, Pelloski CE, et al. Management of complex breast cysts. Am J Roentgenol. 1999;173:1331-1336.
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