What are the current indications for total parotidectomy?

  • Intraparotid lymph node metastases from an extraparotid tumor, usually skin neoplasms (e.g., basal cell carcinoma, melanoma, squamous cell carcinoma, Merkel cell carcinoma, etc.)
    • Regardless of the lobe in which the metastasis is found, but strictly necessary in those located in the deep lobe
  • Intraparotid lymph node metastasis from a primary tumor of the parotid gland:
    • Regardless of the lobe in which the metastasis is identified, but strictly necessary in those located in the deep lobe
  • Primary parotid gland tumor with metastasis to regional cervical nodes [N+]
  • High-grade malignant primary tumor of the parotid gland with known high risk of regional lymph node metastasis
  • Malignant primary tumor of the deep lobe of the parotid gland
  • Benign primary tumor of the superficial lobe with extension to the deep lobe:
    • The latter scenario is usually managed, in most cases, by superficial parotidectomy associated with a partial excision of the deep lobe
  • Benign primary tumor of the deep lobe requiring a superficial parotidectomy “of necessity” for excision (in other words, those in which it is not possible to perform a deep parotidectomy while preserving the superficial lobe)
  • Malignant primary tumor of the parotid gland with invasion of surrounding soft tissues
  • Primary tumor of the parotid gland with a high rate of multifocality (to ensure complete removal, e.g., oncocytomas).
  • Bibliography:
  1. Olsen KD, Moore EJ. (2014) Deep lobe parotidectomy: clinical rationale in the management of primary and metastatic cancer. Eur Arch Otorhinolaryngol. 271(5):1181-5.
  2. Olsen KD, Quer M, de Bree R, Vander Poorten V, Rinaldo A, Ferlito A. (2017) Deep lobe parotidectomy-why, when, and how? Eur Arch Otorhinolaryngol. 274(12):4073-4078.
  3. Thom JJ, Moore EJ, Price DL, Kasperbauer JL, Starkman SJ, Olsen KD. (2014) The Role of Total Parotidectomy for Metastatic Cutaneous Squamous Cell Carcinoma and Malignant Melanoma. JAMA Otolaryngol Head Neck Surg. 140(6):548-54.

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