What proportion of people with cancer have a heritable genetic risk factor?

Samadder NJ, et al. JAMA Oncol. 2021;7(2):230‑237. doi:10.1001/jamaoncol.2020.6252

One in 8 people with cancer have a gene variant that increases cancer risk and can be passed down through their family.

While many genetic changes called “gene variants’’ are good for your health, or simply make you unique, others can increase the risk of developing different types of cancers, including colon, breast, stomach, uterine, skin, prostate, ovarian, and pancreatic cancers. Like other genetic information, variants that increase the risk for cancer can be passed down from a family member. This can lead to hereditary cancer.

Leave a comment