Radiographic Image of Medullary Carcinoma of the Breast

  • The sonographic image for this patient shows a fairly round, well-circumscribed, microlobulated lesion with posterior enhancement
  • The most reliable sonographic feature of medullary carcinoma is:
    • Enhanced through transmission:
      • This results from the highly cellular lesion with a paucity of desmoplastic fibrous tissue, in addition to areas of cystic necrosis and hemorrhage
    • Medullary carcinomas:
      • Are classically well-circumscribed:
        • Though most of them have some area of angularity
    • High-grade, colloid (mucinous), and papillary carcinomas:
      • Typically have a sonographic appearance similar to medullary carcinoma:
  • The lesion in Image:
    • Is irregular, has spiculated margins, and shows posterior shadowing:
      • All of these features are commonly seen in fat necrosis, scar, and low-grade invasive cancers
  • Hematoma is unlikely to have enhanced through transmission
  • References:
    • Harvey JA. Unusual breast cancers: useful clues to expanding the differential diagnosis. Radiology. 2007;242(3):683-694.
    • Meyer JE, Amin E, Lindfors KK, Lipman JC, Stomper PC, Genest D. Medullary carcinoma of the breast: mammographic and US appearance. Radiology. 1989;170(1 Pt 1):79-82.
    • Stavros AT. Malignant solid breast nodules: specific types. In: Stavros AT. Breast Ultrasound. Philadelphia, PA: Lippincott Williams & Wilkins; 2004:297-688.
#Arrangoiz #BreastSurgeon #CancerSurgeon #SurgicalOncologist #MountSinaiMedicalCenter #Miami #Mexico

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