👉The goal of risk management in mutation carriers is to reduce the probability of developing a breast cancer or to diagnose a breast cancer early when it can be treated with the best outcome and least morbidity.
👉The primary options for managing cancer risk include enhanced surveillance, chemoprevention, and prophylactic surgery.
👉Certain reproductive and lifestyle factors may also modify breast cancer risk in gene mutation carriers.
👉Most available data are derived from studies in BRCA1 and BRCA2 gene mutation carriers and may not be relevant to every inherited predisposition syndrome.