Should Patients Undergoing Prophylactic Mastectomy Undergo Sentinel Lymph Node Biopsy (SLNB)?

 

👉Prophylactic mastectomy rates are rapidly rising in the United States.

👉Prophylactic mastectomy may be associated with a 3.5 to 5% occurrence of occult carcinoma depending on the indication for the operation.

👉 SLNB at the time of prophylactic mastectomy may eliminate the need for axillary lymph node dissection (ALND) if occult disease is identified.

👉A recent meta-analysis reviewed 14 studies where SLNB was routinely performed for prophylactic mastectomy in patients undergoing bilateral mastectomy for unilateral cancer.

👉This study found metastatic disease in the SLNB of the prophylactic mastectomy in 0% to 4% of patients with contralateral cancer.

👉The majority of metastatic disease was associated with contralateral axillary tumor spread from the primary tumor, not an occult primary tumor.

👉In patients who were found to have occult malignancy in the prophylactic mastectomy breast, less than 1% of sentinel lymph nodes were positive for metastatic disease.

👉Given the low rates of occult malignancy and axillary metastasis, SLNB is not indicated for patients undergoing prophylactic mastectomy.

👉Rodrigo Arrangoiz MS, MD, FACScirujano oncology y miembro de Sociedad Quirúrgica S.C en el America British Cowdray Medical Center en la ciudad de Mexico:

  • Es experto en el manejo del cáncer de mama.

Training:

• General surgery:

• Michigan State University:

• 2004 al 2010

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• Fox Chase Cancer Center (Filadelfia):

• 2010 al 2012

• Masters in Science (Clinical research for health professionals):

• Drexel University (Filadelfia):

• 2010 al 2012

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• IFHNOS / Memorial Sloan Kettering Cancer Center:

• 2014 al 2016

#Arrangoiz

#Surgeon

#Cirujano

#SurgicalOncologist

#CirujanoOncologo

#BreastSurgeon

#CirujanodeMama

#CancerSurgeon

#CirujanodeCancer

Leave a comment