Ameloblastoma Part 1

  • Ameloblastoma is an aggressive odontogenic tumor:
    • That forms from odontogenic epitheliumwithin a mature fibrous stroma devoid of odontogenic ectomesenchyme.
  • Although classified as a benign tumor:
    • Ameloblastoma is also the most common odontogenic tumor of epithelial origin with severe clinical implications.
  • Ameloblastoma has a locally aggressive growth pattern:
    • About 70% of cases undergo malignant transformation
    • Up to 2% metastasize to other sites
  • Ameloblastoma:
    • Constitutes about 14% of all jaw tumors and cysts
    • It is the most prevalent odontogenic tumors in developing countries
    • The global incidence of ameloblastoma is:
      • 0.5 cases per million persons per year:
        • It is a the most common odontogenic tumor in:
          • Africa and China
        • In the Western hemisphere:
          • Ameloblastoma is second to odontoma as the most common odontogenic tumor:
            • But the African American population is five times more likely to develop ameloblastoma compared to the Caucasian population.
    • Most patients with ameloblastoma:
      • Are between ages 30 and 60 years:
        • But average age at time of diagnosis varies from continent to continent estimated to be approximately:
          • 42.3 and 30.4 years in Europe and Africa, respectively.
    • Only 10% to 15% of ameloblastoma cases occur in the pediatric population:
      • But this can be as high as 25% in Africa and Asia
  • Ameloblastoma histologically:
    • Resembles the enamel organ of a developing tooth that has no intention of forming dental hard tissues:
      • Because the stroma lacks the properties of dental mesenchyme.
    • Despite the similarities:
      • It is intriguing that ameloblastoma still displays a distinctive clinically invasive and aggressive growth pattern
  • Due to naivety and limited healthcare facilities, ameloblastoma patients in developing countries often present with massively grown lesions before seeking care

Presentation1

Rodrigo Arrangoiz MS, MD, FACS miembro de Sociedad Quirúrgica S.C. realiza cirugía de cabeza y cuello / cirugía endocrina / cirugía oncológica en el America British Cowdray Medical Center en Mexico:

 

prof_739_20190417135234

Entrenamiento:

• General surgery:

• Michigan State University:

• 2004 al 2010

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• Fox Chase Cancer Center (Filadelfia):

• 2010 al 2012

• Masters in Science (Clinical research for health professionals):

• Drexel University (Filadelfia):

• 2010 al 2012

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• IFHNOS / Memorial Sloan Kettering Cancer Center:

• 2014 al 2016

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#OralCavityCancer

#Melanoma

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