Radiation Therapy in Ductal Carcinoma In Situ of the Breast (DCIS)

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  • Studies continue to evaluate for a subset of patients with DCIS who may not require adjuvant radiation therapy following breast-conserving surgery:In a prospective nonrandomized trial, ECOG E5194:Evaluated two cohorts of patients:Group 1 had ≤ 2.5-cm low- and intermediate-grade DCIS
        • Group 2 had ≤ 1 cm high-grade DCISBoth cohorts had margins of at least 3 mm and did not receive adjuvant radiation therapyTamoxifen was given to 30% of patients:Local recurrence at 5 years was: 6.1% in group 1
              • 15.3% in group 2
            • The rate of local recurrence at 12 years was: 14.4% in group 124.6% in group 2. There was no plateau in the incidence of local recurrence over time.
    • The Radiation Therapy Oncology Group (RTOG) 9804 study:Randomized patients with < 2.5 cm low- and intermediate-grade DCIS and margins ≥3 mm to adjuvant radiation or no radiation therapy following partial mastectomy:Seven-year outcomes demonstrated an increase in local recurrence with the omission of radiation therapy:6.7% vs 0.9%
        • Tamoxifen was given to 62% of patients.
    • Similar outcomes were also noted in the Dana Farber prospective trial of excision alone

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Rodrigo Arrangoiz MS, MD, FACS a surgical oncologist and is a member of Sociedad Quirúrgica S.C at the America British Cowdray Medical Center in Mexico City:

  • He is an expert in the management of breast cancer.

    • If you have any questions about DCIS and radiation therapy please fill free to contact Dr. Arrangoiz.

Training:

• General surgery:

• Michigan State University:

• 2004 al 2010

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• Fox Chase Cancer Center (Filadelfia):

• 2010 al 2012

• Masters in Science (Clinical research for health professionals):

• Drexel University (Filadelfia):

• 2010 al 2012

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• IFHNOS / Memorial Sloan Kettering Cancer Center:

• 2014 al 2016

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http://www.sociedadquirurigca.com

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