Triple-Negative Breast Cancers (TNBCs)

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  • Triple-negative breast cancers (TNBCs):
    • Negative for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2.
    • They account for approximately 15% to 20% of all female breast cancers.
    • TNBC is heterogeneous based on gene expression microarray, and identification of TNBC subtypes and their behavior has the potential to enable more targeted, neoadjuvant, and adjuvant interventions.
    • TNBCs usually are higher grade (Nottingham score 3) and are more common in younger, Hispanic, and African American women.
    • They are more aggressive, have an increased likelihood of distant disease and mortality.
    • They are larger at presentation, and are more likely to be associated with lymph node metastases.
    • Patients with TNBC are at a higher risk for visceral metastases early in the course of the disease.
    • Genetic risk evaluation is recommended for patients with TNBC diagnosed at or before 60 years of age.
    • Surgical management may be influenced by gene testing results.
    • Standard adjuvant chemotherapy is anthracycline or taxane based.

TNBC-slide2_0

 

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Rodrigo Arrangoiz MS, MD, FACS a surgical oncologist and is a member of Sociedad Quirúrgica S.C at the America British Cowdray Medical Center in Mexico City:

  • He is an expert in the management of breast cancer.

    • If you have any questions about the management of triple negative breast cancer patients please fill free to contact Dr. Arrangoiz.

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Training:

• General surgery:

• Michigan State University:

• 2004 al 2010

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• Fox Chase Cancer Center (Filadelfia):

• 2010 al 2012

• Masters in Science (Clinical research for health professionals):

• Drexel University (Filadelfia):

• 2010 al 2012

• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:

• IFHNOS / Memorial Sloan Kettering Cancer Center:

• 2014 al 2016

#Arrangoiz

#Surgeon

#Cirujano

#SurgicalOncologist

#CirujanoOncologo

#BreastSurgeon

#CirujanodeMama

#CancerSurgeon

#CirujanodeCancer

http://www.sociedadquirurigca.com

 

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