
- In 2014, The American Society of Clinical Oncology (ASCO) Guidelines were updated and published on the use of SLNB for early-stage breast cancer:
- A strong recommendation was made for re-operative SLNM and SLNB in women who have undergone prior breast or axillary surgery.
- There are now multiple reports of successful second SLNM and SLNB in patients with a local breast cancer recurrence following a previous SLNB or even axillary lymph node dissection (ALND):
- In a recent systematic review and meta-analysis of studies on repeat SLNB in locally recurrent breast cancer found that sentinel node identification was successful in 452 of the 692 patients (65.3%):
- This percentage was significantly higher in patients who had undergone previous SLNB compared to previous ALND:
- 81.0% vs 52.2%.
- In most of these studies, a dual tracer technique, with use of blue dye and radiocolloid, was performed.
- Aberrant drainage pathways were demonstrated in 43% of patients:
- More frequently after previous ALND than after previous SLNB:
- 69.2% vs 17.4%.
- Lymphoscintigraphy, including examination of the contralateral axilla:
- Should be performed if repeat SLNB is planned:
- Given that these patients often have alternate drainage patterns.
- Should be performed if repeat SLNB is planned:
- More frequently after previous ALND than after previous SLNB:
- This percentage was significantly higher in patients who had undergone previous SLNB compared to previous ALND:
- In a recent systematic review and meta-analysis of studies on repeat SLNB in locally recurrent breast cancer found that sentinel node identification was successful in 452 of the 692 patients (65.3%):



REFERENCES
- Lyman GH, Temin S, Edge SB, et al. Sentinel lymph node biopsy for patients with early-stage breast cancer: American Society of Clinical Oncology Clinical Practice Guideline update. J Clin Oncol. 2014; 32:1365-1383.
- Maaskant-Braat AJ, Voogd AC, Roumen RM, et al. Repeat sentinel node biopsy in patients with locally recurrent breast cancer: a systematic review and meta-analysis of the literature. Breast Cancer Res Treat. 2013;138:13-20.
Rodrigo Arrangoiz MS, MD, FACS a surgical oncologist and is a member of Sociedad Quirúrgica S.C at the America British Cowdray Medical Center in Mexico City:
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He is an expert in the management of breast cancer.
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If you have any questions about SLNM and SLNB is recurrent breast cancer please fill free to contact Dr. Arrangoiz.
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Training:
• General surgery:
• Michigan State University:
• 2004 al 2010
• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:
• Fox Chase Cancer Center (Filadelfia):
• 2010 al 2012
• Masters in Science (Clinical research for health professionals):
• Drexel University (Filadelfia):
• 2010 al 2012
• Surgical Oncology / Head and Neck Surgery / Endocrine Surgery:
• IFHNOS / Memorial Sloan Kettering Cancer Center:
• 2014 al 2016
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#Surgeon
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#BreastSurgeon
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