Oral Cavity Cancer

The most important histological feature of the primary tumor that affects selection of treatment and eventual prognosis is its depth of infiltration.

  • Thin and superficially invasive lesions have a lower risk of regional lymph node metastasis, are highly curable, and offer an excellent prognosis.

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  • On the other hand, thicker lesions that deeply infiltrate the underlying soft tissues have a significantly increased incidence of regional lymph node metastasis and an adverse impact on prognosis.

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The risk of lymph node metastasis and survival rates in relation to the thickness of the primary lesion for T1 and T2 squamous carcinomas of the oral tongue and floor of mouth are shown in the following figure:

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Although it would be ideal to know the exact thickness of the lesion before surgical intervention, in many instances having that information before surgical excision of the primary tumor is clinically impractical.

  • In general, however, thickness of the lesion as appreciated by palpation is a reasonably good indicator of deeply invasive lesions versus superficial lesions to estimate the extent of soft tissue and/or bone resection for the primary lesion and to decide on the need for elective dissection of the regional lymph nodes at risk in a neck with negative clinical findings.

Rodrigo Arrangoiz MS, MD, FACS
Cirugía General y Gastrointestinal
Michigan State University
Cirugía Oncológica
Fox Chase Cancer Center
Tumores de Cabeza y Cuello / Cirugía Endocrina
Fox Chase Cancer Center
Tumores de Cabeza y Cuello / Cirugía Endocrina
IFHNOS / Memorial Sloan Kettering Cancer Center
Maestría en Ciencias de Investigación
Drexel University
Certificado por el Colegio Americano de Cirugía
Fellow del Colegio Americano de Cirugía
Fellow de la Sociedad de Cirugia Oncológica 

Sociedad Quirúrgica S.C.
Hospital ABC Santa Fé
Av. Carlos Graef Fernández #154

Consultorio 515
Col. Tlaxala, Delg. Cuajimalpa
México, D.F. 05300
Tel: 1103 – 1600 Ext 4515 a la 4517
Fax:1664 – 7164
 

 

 

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