- The staging of primary tumors of the oral cavity:
- As published by the AJCC and UICC is widely accepted
- In its most recent revision (eighth edition of the AJCC Staging Manual):
- Depth of invasion (DOI) is added to the surface dimensions and local extent of the tumor:
- As the required parameters for primary tumor staging in the oral cavity
- Depth of invasion (DOI) is added to the surface dimensions and local extent of the tumor:

parameters required for T staging of oral cancer
- Accurate assessment of DOI by clinical examination is not possible:
- However, the staging system stratifies DOI by 5 mm increments, and thus clinical estimates of DOI can be categorized into:
- Thin (less than 5 mm)
- Thick (5 to 10 mm)
- Very thick (greater than10 mm)
- By palpation to assign clinical T stage
- However, the staging system stratifies DOI by 5 mm increments, and thus clinical estimates of DOI can be categorized into:

thick, and very thick by palpation
- The stage distribution of patients with squamous cell carcinoma of the oral cavity at the Memorial Sloan Kettering Cancer Center in New York is shown in the graph:

(MSKCC data 1985 to 2015)
