Breast Cancer Recurrence after Mastectomy

The main goal of routine post-treatment follow-up is the early detection of local-regional recurrence.

For patients with locally recurrent breast cancer, that appears to be confined to the soft tissue of the chest wall, and no evidence of metastatic disease. When possible, surgical resection of the tumor is the initial treatment of choice for most patients.

Following surgery, the addition of radiation therapy appears to further decrease the risk of a subsequent local recurrence. The addition of adjuvant systemic therapy should be considered for patients who suffer local recurrence with more than minimal tumor burden.

Aebi S, Wapnir I. Management of locoregional recurrences. In: Winchester D J, Winchester D P, Hudis C A, and Norton L eds. Breast Cancer 2nd ed. Hamilton, Canada: B C Deker, Inc; 2006:511-523.

Buchanan C L, Dorn P L, Fey J, et al. Locoregional recurrence after mastectomy: incidence and outcomes. J Am Coll of Surg. 2006;203:469-474.

Dahlstrøm K K, Andersson A P, Andersen M, Krag C. Wide local excision of recurrent breast cancer in the thoracic wall. Cancer. 1993;72:774-777.

National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology. Breast Cancer. Available at

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